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M94A2732.TXT
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1994-10-25
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Document 2732
DOCN M94A2732
TI Several CD4/CD8 ratio values in HIV-infected children with negative-, or
positive-p24-antigenaemia.
DT 9412
AU Voiculescu C; Avramescu C; Balasoiu M; Faculty of Medicine Craiova,
Romania.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):237 (abstract no. PB0379). Unique
Identifier : AIDSLINE ICA10/94369843
AB OBJECTIVE: Statement of different CD4/CD8 ratio values in HIV-infected
children, related to the presence of the absence of p24-antigenaemia.
METHODS: 1. Patients. 40 HIV-seropositive children (4 to 5 yrs old),
with bacteriologically confirmed respiratory or intestinal opportunistic
infections, were subdivided into the following
subgroups:a.p24-antigenaemia+, p24-antibody-, hypogammaglobulinaemia;
b.p24-antigenaemia+,p24-antibody+, hypergammaglobulinaemia;
c.p24-antigenaemia-,p24-antibody+, hypergammaglobulinaemia. 2. Sooring
of CD4/CD8 ratios. Blood lymphocytes, among a-,b-, and c-subgroups, were
studied, concerning CD4 and CD8 amounts, by means of flow cytometry
(BECTON DICKINSON FACSort), in the presence of appropriated monoclonals.
Ranges of CD4/CD8 ratios were expressed in median with 25 to 75
percentils. RESULTS: The following CD4/CD8 ranges were present,
respectively:a-subgroup:from 0.120 to 0.326; b-subgroup:from 0.534 to
0.615; c-subgroup:from 0.527 to 0.700.
DE Agammaglobulinemia/IMMUNOLOGY AIDS-Related Opportunistic
Infections/DIAGNOSIS/IMMUNOLOGY Child, Preschool *CD4-CD8 Ratio
Female Human Hypergammaglobulinemia/IMMUNOLOGY HIV Core Protein
p24/*BLOOD HIV Infections/*DIAGNOSIS/IMMUNOLOGY HIV
Seronegativity/*IMMUNOLOGY Male MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).